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Establishment and drug sensitivity evaluation of murine ascites hepatocarcinoma cell line with high lymphatic

Hongying ZHANG, Jianwu TANG, Wenting ZHU, Chunxiu HU, Guowang XU

Frontiers of Medicine 2009, Volume 3, Issue 2,   Pages 119-129 doi: 10.1007/s11684-009-0022-9

Abstract: In order to provide a sensitive cell line model for investigating the mechanisms underlying the lymphaticline with high lymphatic metastatic potential (Hca-P/L ) was established and the effect of curcumininoculated into the medioventral line of a mouse 615 and the first generation of metastatic tumor cellsproliferation of Hca-P and Hca-P/L was observed by inverted microscope, cell growth curve and cellHca-P/L is a novel sensitive cell line model for investigating the mechanisms underlying tumor lymphatic

Keywords： murine ascites hepatocarcinoma cell line     metastasis     curcumin     drug sensitivity    

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Impact of siRNA targeting pirh2 on proliferation and cell cycle control of the lung adenocarcinoma cellline A549

SU Yuan, JIN Yang, ZHANG Xiaoju, ZHOU Qiong, BAI Ming, ZHU Liping

Frontiers of Medicine 2007, Volume 1, Issue 4,   Pages 359-363 doi: 10.1007/s11684-007-0069-4

Abstract: cycle control of the lung cancer cell line A549.Cell proliferation was assessed by cell counting kit-8 (CCK-8).Taken together, the inhibition of pirh2 expression in the lung adenocarcinoma cell line A549 resultedin reduced tumor cell growth via the inhibition of cell proliferation, the activation of apoptosis andthe interruption of cell cycle transition.

Keywords： control     interruption     cytoplasm     number     growth    

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Natural killer cell lines in tumor immunotherapy

Min Cheng, Jian Zhang, Wen Jiang, Yongyan Chen, Zhigang Tian

Frontiers of Medicine 2012, Volume 6, Issue 1,   Pages 56-66 doi: 10.1007/s11684-012-0177-7

Abstract: However, cancers are able to develop mechanisms to escape NK cell attack or to induce defective NK cellsCurrent NK cell-based cancer immunotherapy is aimed at overcoming NK cell paralysis through several potentiallines and genetically modifying fresh NK cells or NK cell lines.The stable allogeneic NK cell line approach is more practical for quality-control and large-scale productionIn this review, NK cells in tumor immunotherapy are discussed, and a list of therapeutic NK cell lines

Keywords： natural killer cell     natural killer cell line     tumor immunotherapy     genetic modification    

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Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 766-772 doi: 10.1007/s11684-021-0916-8

Abstract: Patients with small-cell lung cancer (SCLC) relapse within months after completing previous therapiesThis study aimed to investigate the efficacy and safety of anlotinib as third- or further-line therapyFor patients with short-term relapsed SCLC, third- or further-line anlotinib treatment was associated

Keywords： anlotinib     chemotherapy     short-term relapsed     small-cell lung cancer    

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Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cellline via ERKs pathway

Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,

Frontiers of Medicine 2010, Volume 4, Issue 1,   Pages 106-111 doi: 10.1007/s11684-010-0004-y

Abstract: investigate the extracellular regulated protein kinases (ERKs) pathway of HBx on glomerular mesangial cellPCI-neo containing HBV X gene (pCI-neo-X) was then transfected into cultured GMC line via liposome.HBx upregulates TNF-α expression and induces cell proliferation of GMC line partly through ERK signal

Keywords： hepatitis B virus     X gene     glomerular mesangial cell line     extracellular regulated protein kinases     tumor    

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Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60

Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU

Frontiers of Medicine 2010, Volume 4, Issue 3,   Pages 323-328 doi: 10.1007/s11684-010-0026-5

Abstract: nuclear factor-kappa B (NF-κB) inhibitor Bay 11-7082 on Fas/FasL system and Fas-mediated apoptosis in cellline HL-60 cells.

Keywords： nuclear factor-kappa B     Fas/FasL system     HL-60     Bay 11-7082    

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High-level expression of recombinant IgG1 by CHO K1 platform

Ningning Xu, Jianfa Ou, Al-Karim (Al) Gilani, Lufang Zhou, Margaret Liu

Frontiers of Chemical Science and Engineering 2015, Volume 9, Issue 3,   Pages 376-380 doi: 10.1007/s11705-015-1531-5

Abstract: The Chinese Hamster Ovary (CHO K1) cell was used to express a targeted anti-cancer monoclonal antibodyby optimizing the platform of the construction of production cell line in this study.Post transfection, the production of cell pool was optimized by glutamine-free selection and amplificationThe best cell pool of CHO K1/IgG1 was used to screen the top single clone using the limiting dilutionThis study demonstrated that the construction of high producing cell line, from gene to clone, could

Keywords： Chinese hamster ovary (CHO)     monoclonal antibody     IgG1     amplification     cell line development    

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In vivo imaging of hematopoietic stem cell development in the zebrafish

Panpan Zhang, Feng Liu

Frontiers of Medicine 2011, Volume 5, Issue 3,   Pages 239-247 doi: 10.1007/s11684-011-0123-0

Abstract: imaging is crucial for developmental biology and can further help to follow cell development/differentiationhas facilitated tracing of the developmental dynamics of a specific organ, tissue, or even a single cell

Keywords： hematopoietic stem cell     hematopoiesis     in vivo imaging     transgenics     zebrafish    

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Consideration on the Development Strategy of High-speed Maglev in China

Yan Luguang

Strategic Study of CAE 2002, Volume 4, Issue 12,   Pages 40-46

Abstract: From the practical development needs and real situation of the passenger transport in China, based onanalysis of the international progress, after quite serious discussion, since 1998 a suggestion for the developmentConstruction of a short test and operational demonstration line based on the imported technology, c.Feasibility study for long distance operational line and organization of the internal R & D and engineeringConstruction of a long distance operational line and commercialization of the equipmens and engineering

Keywords： high-speed maglev     development strategy     Shanghai demonstration line     long distance line feasibility    

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Acoustic fault signal extraction via the line-defect phononic crystals

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 1,   Pages 10-10 doi: 10.1007/s11465-021-0666-y

Abstract: In this paper, 2D line-defect phononic crystals (PCs) consisting of periodic acrylic tubes with slitThe defect band, namely, the formed resonance band of line-defect PCs enables the incident acoustic waveThe effectiveness of weak harmonic and periodic impulse signal detection via line-defect PCs are investigatedAll the numerical and experimental results indicate that line-defect PCs can be well used for extracting

Keywords： phononic crystals     line-defect     fault signal extraction     acoustic enhancement    

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Calculations of narrow-band transimissities and the Planck mean absorption coefficients of real gases using line-by-line

Huaqiang CHU, Mingyan GU, Huaichun ZHOU, Fengshan LIU

Frontiers in Energy 2014, Volume 8, Issue 1,   Pages 41-48 doi: 10.1007/s11708-013-0292-4

Abstract: the band parameters of Soufiani and Taine, the more recent parameters of André and Vaillon, and the line-by-line

Keywords： transimissity     HITEMP     HITRAN     Planck mean absorption coefficients    

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The research and development of biomass fuel pellets production line and key manufacturing technology

Zhu Dianxiang

Strategic Study of CAE 2014, Volume 16, Issue 4,   Pages 13-16

Abstract: basis，the large-scale(annual output of 2.0×105 t) and low-cost wood-pellet production lineis completed finally，which has an important demonstration significance to promote the healthy development

Keywords： biomass fuel pellet     combustion performance     energy conservation and emissions reduction     production line    

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Pareto lexicographic α-robust approach and its application in robust multi objective assembly line balancing

Ullah SAIF,Zailin GUAN,Baoxi WANG,Jahanzeb MIRZA

Frontiers of Mechanical Engineering 2014, Volume 9, Issue 3,   Pages 257-264 doi: 10.1007/s11465-014-0294-x

Abstract: application of the proposed method on a simple problem of multi objective optimization of simple assembly line

Keywords： Pareto     lexicographic α-robust     assembly line balancing    

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The industrialization problems of electric vehicles in China

Guo Konghui

Strategic Study of CAE 2011, Volume 13, Issue 9,   Pages 4-7

Abstract:

The characteristics and development situation of electric vehicles areelectric are characteristics of electric vehicles, and cost, life and weight are the key points to the developmentFinally, the line of electric vehicles development is given: market guiding, supporting small and helpinglarge, taking low-end as cut point, and diverse development.

Keywords： electric vehicles     industrialization     strategic choice     development line    

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Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Frontiers of Agricultural Science and Engineering 2019, Volume 6, Issue 1,   Pages 33-41 doi: 10.15302/J-FASE-2018228

Abstract: Meanwhile, early embryo development is significant for somatic cell nuclear transfer in cattle as a largeprocess occurring after fertilization and critical roles of epigenetic modifiers during preimplantation developmenttools also presents an alternative approach to the functional annotation of genes critical to early development

Keywords： bovine cloning     embryo development     somatic cell nuclear transfer     X-inactive specific transcript    

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Title Author Date Type Operation

Establishment and drug sensitivity evaluation of murine ascites hepatocarcinoma cell line with high lymphatic

Hongying ZHANG, Jianwu TANG, Wenting ZHU, Chunxiu HU, Guowang XU

Journal Article

Impact of siRNA targeting pirh2 on proliferation and cell cycle control of the lung adenocarcinoma cellline A549

SU Yuan, JIN Yang, ZHANG Xiaoju, ZHOU Qiong, BAI Ming, ZHU Liping

Journal Article

Natural killer cell lines in tumor immunotherapy

Min Cheng, Jian Zhang, Wen Jiang, Yongyan Chen, Zhigang Tian

Journal Article

Anlotinib as third- or further-line therapy for short-term relapsed small-cell lung cancer: subgroup

Journal Article

Hepatitis B virus X protein upregulates tumor necrosis factor-α expression of rat mesangial cellline via ERKs pathway

Hong-Zhu LU MD, Dan LIU BM, Qi-Hong FAN BM, Jian-Hua ZHOU MD,

Journal Article

Inhibition of NF-kappa B can enhance Fas-mediated apoptosis in leukemia cell line HL-60

Li WANG, Shi ZHAO, Hong-Xiang WANG, Ping ZOU

Journal Article

High-level expression of recombinant IgG1 by CHO K1 platform

Ningning Xu, Jianfa Ou, Al-Karim (Al) Gilani, Lufang Zhou, Margaret Liu

Journal Article

In vivo imaging of hematopoietic stem cell development in the zebrafish

Panpan Zhang, Feng Liu

Journal Article

Consideration on the Development Strategy of High-speed Maglev in China

Yan Luguang

Journal Article

Acoustic fault signal extraction via the line-defect phononic crystals

Journal Article

Calculations of narrow-band transimissities and the Planck mean absorption coefficients of real gases using line-by-line

Huaqiang CHU, Mingyan GU, Huaichun ZHOU, Fengshan LIU

Journal Article

The research and development of biomass fuel pellets production line and key manufacturing technology

Zhu Dianxiang

Journal Article

Pareto lexicographic α-robust approach and its application in robust multi objective assembly line balancing

Ullah SAIF,Zailin GUAN,Baoxi WANG,Jahanzeb MIRZA

Journal Article

The industrialization problems of electric vehicles in China

Guo Konghui

Journal Article

Factors affecting early embryonic development in cattle: relevance for bovine cloning

Yanna DANG, Kun ZHANG

Journal Article